The Snack That Turned Mice Transparent: What’s Really Hiding in Our Food?

This story begins with a mouse, and not a magical one in gloves or a cartoon (although who doesn’t love Mickey?) No, I’m talking about a real, living, breathing mouse that slowly…vanishes.

While I am queen of the metaphor, this isn’t one. Earlier this year at Stanford, mice bodies started to grow translucent, organs shimmering beneath thin skin, veins and bones glowing like neon threads beneath a synthetic sky.

It’s a side effect of tartrazine, a synthetic yellow dye found in the neon glow of cheese puffs, Doritos, and neon drinks you drank without thinking twice about it.

It raises a question that’s been waiting in your pantry for years that most of us tend to ignore. What exactly are we eating?

The Stanford Study That Shook Us

In early 2025, scientists at Stanford University published data on the effects of tartrazine (also known as Yellow No. 5) on laboratory mice.

Without any of the drama I was trying to put into this story, the mice given consistent doses of tartrazine didn’t just experience inflammation or behavioral shifts, as has been documented before. Nope, their bodies began turning translucent.

The dye, reacting with cellular processes under specific conditions, began altering the way light scattered through their tissues…especially in young or metabolically active mice. Which is good because we never give our children anything that’s neon in color or bright yellow to drink…right?

In essence, the chemical hijacked the body’s visibility. If this happens to a mouse, what does it do to us?

Tartrazine is a synthetic azo dye derived from petroleum. That’s right…your favorite orange snack dust is chemically akin to what fuels your car. Makes sense that at some point in time someone out there decided it would be totally cool to eat a bunch of it. My money is on the pharmaceutical companies who benefit the most from this, but of course, that’s neither here nor there.

You’ll find this glorious yellow stuff in cheese puffs, mac and cheese, Cheetos, yellow sodas (shout out to Mountain Dew), lemon-flavored candies, instant noodles, popsicles, and even certain supplements and cosmetics.

It’s used to give food that bright, artificial joy, a color too cheerful to question. I mean…what’s wrong with something the color of a smiley face?

Here’s the thing though: tartrazine has long been controversial. It’s banned in several European countries, and tons of studies have linked it to hyperactivity, asthma, migraines, and autoimmune reactions. It’s been shown to disrupt mitochondrial function in animal models for a long time.

Now we know it can alter tissue translucency. Still, in the U.S., it remains FDA-approved.

A Cheese Puff Is a Chemical Dream

The typical orange corn puff that we all know and love contains enriched cornmeal (stripped of nutrients, then re-added artificially). Don’t get me started on what “enriched” means in this country…we literally use a word that’s supposed to be better to explain stuff that’s a lot worse for you. Why I switched from American flour to Italian flour (read this). Anyway, back to my rant, vegetable oils (often hydrogenated, oxidized), artificial cheese flavor (which contains no cheese at all), flavor enhancers like MSG, preservatives like BHT or TBHQ, and colorants like Yellow No. 5 and No. 6. That’s what’s in your favorite little late-night snack.

It is a chemical cocktail, crafted for mouthfeel, crunch acoustics, flavor overload, and addictive texture. It’s engineered, not cooked. Somehow though, it’s marketed as food.

What does it do inside us is the big scary question that we don’t like looking at too closely. We don’t fully know either, but mice are already telling us.

Food dyes like tartrazine aren’t metabolized like nutrients. They’re absorbed, stored, and sometimes interfere with your immune system, liver function, hormonal balance, or even your neurotransmitter signaling.

Some mimic estrogen, while some are stored in fat, some even cross the blood-brain barrier we talk about being sacred. In sensitive individuals (especially children) the results can be dramatic with ADHD-like symptoms, skin rashes, sleep disturbances, mood swings, and even asthma attacks.

Still, they remain common in the American food supply.

If you’re like me and read this and was like, “dude, why?”, it’s because color sells.

In Europe, foods containing tartrazine must carry a warning label stating: “May have an adverse effect on activity and attention in children.”

In the U.K., many companies replaced it with natural alternatives like beta carotene or paprika extract, but in the U.S. tartrazine is business as usual.

Lobbying power of food giants is the big one that no one wants to talk about, but we also have a regulatory system built on proof of harm, not precaution. Our system is founded on the belief that small doses are “safe” despite long-term accumulation studies being rare.

Honestly though, there’s no appetite for change. Why reform your snacks when it’s cheaper to dye them? It’s not like anyone seems to care what they’re eating, or they would’ve stopped buying them long ago.

Transparency vs. Translucency

Ironically, the mouse that turned clear is a metaphor for something else: transparency in our food system.

We don’t have it, not even a little. We’re told ingredients are “generally recognized as safe,” but rarely told how they’re made, what the long-term studies say, or how they go about and interact in combination with other stuff. We trust that if it’s on the shelf, it’s safe.

But the FDA has approved artificial dyes derived from coal tar, preservatives linked to tumors in rats, sweeteners with known neurotoxic effects, and additives banned in dozens of countries.

In America, food isn't just nourishment, it's profit.

Tartrazine isn’t alone either.

Red 40 (Allura Red) is linked to hyperactivity, “may” accelerate colon cancer in animals, and is banned in parts of Europe.

Yellow 6 (Sunset Yellow) is associated with adrenal tumors in rats and a known immune system disruptor.

Blue 1 and Blue 2 are linked to brain tumors in mice, and can be absorbed across the blood-brain barrier.

TBHQ (preservative in oils) are closely related to butane (yes, lighter fluid, how fun!) and linked to vision disturbances and DNA fragmentation…not like you need your DNA to be whole for anything anyway.

These ingredients don’t make food better, they just make it last longer, look brighter, and addict you faster.

Related Reads You Might Like:

Want snacks without dyes, preservatives, or additives?

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Because food should feed you…not hide from you.

What We’ve Learned From the Mouse

The mice in the lab didn’t know they were being poisoned. They just ate what they were given, and slowly, invisibly, they changed.

Like us.

We, too, are fed foods laced with synthetics we can’t pronounce, we also assume it’s fine…until something changes.
Our weight maybe goes first, then our focus. Our fertility or our moods take hits before our inflammation gets so out of hand our bodies don’t know what to do about them.

Like the mouse, something inside us is disappearing, too. Change won’t come from the top (it never does), it comes from reading labels, refusing to buy brands that use dyes, supporting local and organic producers, demanding policy change, sharing knowledge (share this article with your friends and family!), and growing what we can

Beneath the neon dust and flavor explosions, our bodies remember what food is supposed to be, honest and real. If we listen to the mice (and to ourselves) maybe it can become visible again.

Michele Edington (formerly Michele Gargiulo)

Writer, sommelier & storyteller. I blend wine, science & curiosity to help you see the world as strange and beautiful as it truly is.

http://www.michelegargiulo.com
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